Adult brain tumors
Adult brain tumors
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Newsfeed display by CaRP Adult brain tumors are diseases in which cancer (malignant) cells begin to grow in the tissues of the brain. The brain controls memory and learning, senses - hearing, sight, smell, taste, and touch, and emotion. It also controls other parts of the body, including muscles, organs, and blood vessels. Tumors that start in the brain are called primary brain tumors.

Often, tumors found in the brain have started somewhere else in the body and spread (metastasized) to the brain. These are called metastatic brain tumors.

A doctor should be seen if the following symptoms appear:
1. Frequent headaches.
2. Vomiting.
3. Loss of appetite.
4. Changes in mood and personality.
5. Changes in ability to think and learn.

Tests that examine the brain and spinal cord are used to detect adult brain tumor. The following tests and procedures may be used:
1. CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.
2. MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves, and a computer to make a series of detailed pictures of the brain and spinal cord. A substance called gadolinium is injected into the patient through a vein. The gadolinium collects around the cancer cells so they show up brighter in the picture. This procedure is also called nuclear magnetic resonance imaging (NMRI).

Adult brain tumor is diagnosed and removed in surgery. If a brain tumor is suspected, a biopsy is done by removing part of the skull and using a needle to remove a sample of the brain tissue. A pathologist views the tissue under a microscope to look for cancer cells. If cancer cells are found, the doctor will remove as much tumor as safely possible during the same surgery. An MRI may then be done to determine if any cancer cells remain after surgery. Tests are also done to find out the grade of the tumor.

The grade of a tumor refers to how abnormal the cancer cells look under a microscope and how quickly the tumor is likely to grow and spread. The pathologist determines the grade of the tumor using tissue removed for biopsy. The following grading system may be used for adult brain tumors:
1. Grade I
2. The tumor grows slowly, has cells that look similar to normal cells, and rarely spreads into nearby tissues. It may be possible to remove the entire tumor by surgery.
3. Grade II
4. The tumor grows slowly, but may spread into nearby tissue and may become a higher-grade tumor.
5. Grade III
6. The tumor grows quickly, is likely to spread into nearby tissue, and the tumor cells look very different from normal cells.
7. Grade IV
8. The tumor grows very aggressively, has cells that look very different from normal cells, and is difficult to treat successfully.
9. The chance of recovery and choice of treatment depend on the type, grade, and location of the tumor and whether cancer cells remain after surgery and/or have spread to other parts of the brain.

No one knows the exact causes of brain tumors. Doctors can seldom explain why one person develops a brain tumor and another does not. However, it is clear that brain tumors are not contagious. No one can "catch" the disease from another person.

Research has shown that people with certain risk factors are more likely than others to develop a brain tumor. A risk factor is anything that increases a person's chance of developing a disease.

The following risk factors are associated with an increased chance of developing a primary brain tumor:
1. Being male—In general, brain tumors are more common in males than females. However, meningiomas are more common in females.
2. Race—Brain tumors occur more often among white people than among people of other races.
3. Age—Most brain tumors are detected in people who are 70 years old or older. However, brain tumors are the second most common cancer in children. (Leukemia is the most common childhood cancer.) Brain tumors are more common in children younger than 8 years old than in older children.
4. Family history—People with family members who have gliomas may be more likely to develop this disease

Being exposed to radiation or certain chemicals at work:
1. Radiation—Workers in the nuclear industry have an increased risk of developing a brain tumor.
2. Formaldehyde—Pathologists and embalmers who work with formaldehyde have an increased risk of developing brain cancer. Scientists have not found an increased risk of brain cancer among other types of workers exposed to formaldehyde.
3. Vinyl chloride—Workers who make plastics may be exposed to vinyl chloride. This chemical may increase the risk of brain tumors.
4. Acrylonitrile—People who make textiles and plastics may be exposed to acrylonitrile. This exposure may increase the risk of brain cancer.

Scientists are investigating whether cell phones may cause brain tumors. Studies thus far have not found an increased risk of brain tumors among people who use cell phones.

Scientists also continue to study whether head injuries are a risk factor for brain tumors.

So far, these studies have not found an increased risk among people who have had head injuries.

Most people who have known risk factors do not get brain cancer. On the other hand, many who do get the disease have none of these risk factors. People who think they may be at risk should discuss this concern with their doctor. The doctor may be able to suggest ways to reduce the risk and can plan an appropriate schedule for checkups.

A tumor that begins in the brain is called a primary brain tumor. In children, most brain tumors are primary tumors. In adults, most tumors in the brain have spread there from the lung, breast, or other parts of the body. When this happens, the disease is not brain cancer. The tumor in the brain is a secondary tumor. It is named for the organ or the tissue in which it began.

Treatment for secondary brain tumors depends on where the cancer started and the extent of the disease.

The symptoms of brain tumors depend on tumor size, type, and location. Symptoms may be caused when a tumor presses on a nerve or damages a certain area of the brain. They also may be caused when the brain swells or fluid builds up within the skull.

These are the most common symptoms of brain tumors:
1. Headaches, usually worse in the morning.
2. Nausea or vomiting.
3. Changes in speech, vision, or hearing.
4. Problems balancing or walking.
5. Changes in mood, personality, or ability to concentrate.
6. Problems with memory.
7. Muscle jerking or twitching including seizures or convulsions.
8. Numbness or tingling in the arms or legs.

These symptoms are not sure signs of a brain tumor. Other conditions also could cause these problems. Anyone with these symptoms should see a doctor as soon as possible. Only a doctor can diagnose and treat the problem.

Living with a serious disease such as a brain tumor is not easy. Some people find they need help coping with the emotional and practical aspects of their disease. Support groups can help. In these groups, patients or their family members get together to share what they have learned about coping with the disease and the effects of treatment. Patients may want to talk with a member of their health care team about finding a support group. Groups may offer support in person, over the telephone, or on the Internet.

People living with a brain tumor may worry about caring for their families, keeping their jobs, or continuing daily activities. Concerns about treatments and managing side effects, hospital stays, and medical bills are also common. Doctors, nurses, and other members of the health care team can answer questions about treatment, working, or other activities. Meeting with a social worker, counselor, or member of the clergy can be helpful to those who want to talk about their feelings or discuss their concerns. Often, a social worker can suggest resources for financial aid, transportation, home care, or emotional support.
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Submitted: 08/04/06

Description: Adult brain tumors are diseases in which cancer (malignant) cells begin to grow in the tissues of the brain. The brain controls memory and learning, senses - hearing, sight, smell, taste, and touch, and emotion. It also controls other parts of the body, including muscles, organs, and blood vessels. Tumors that start in the brain are called primary brain tumors.

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